This database analysis found that approximately one-fourth of patients undergoing initial breast conservation surgery for breast cancer will have a subsequent operative intervention. See also the Invited Commentary by Margenthaler and Vaughan.
Van Osdol et al determine whether all fibroepithelial lesions of the breast require excision to exclude phyllodes tumor.
In a retrospective study covering the past 30 years at a tertiary cancer care institution, Radkani and coauthors review 30 patients with primary breast lymphoma (stage I or II) and analyze the different treatment modalities.
Bagaria et al use as an example the triple-negative phenotype defined by the absence of estrogen
receptor, progesterone receptor, and human epidermal growth factor 2 to examine whether such
inclusion improves the prognostic accuracy of TNM staging for breast cancer.
Matsen and Neumayer provide an overview of current practices for the diagnosis and treatment of breast cancer for surgical practitioners who do not focus on this disease.
Donovan et al determine if variability in clinical presentation at diagnosis correlates with PI3K/Akt mutations in breast cancer stem and progenitor cells (BCSCs) and provides an early prognostic indicator of increased progression and metastatic potential. See the Invited Commentary by Calhoun.