A man had worsening abdominal discomfort and a large recurrent umbilical hernia, early satiety but no nausea or vomiting, night sweats, and weight loss; examination revealed an umbilical hernia, palpable abdominal mass, and lower extremity edema. What is your diagnosis?
This article reviews the pathophysiology, clinical presentation, diagnostic evaluation, and treatment of gastroesophageal reflux disease.
Hoppo et al evaluate use of hypopharyngeal multichannel intraluminal impedance in patients with idiopathic chronic cough to determine whether laryngopharyngeal reflux or high-esophageal reflux was the cause of the cough. See the invited critique by Patti.