This cohort study examines the potential influence of computer-generated mosaic photographs on the diagnosis and management of retinopathy of prematurity.
This observational study describes a software algorithm for determining the margin reflex distances 1 and 2 from facial photographs and evaluates its agreement with manual measurements.
This diagnostic accuracy study compares the grading and quality of optic disc images taken in Kenya by an ophthalmic assistant using a desktop retinal camera vs those taken by non-clinical photographers using a smartphone-based adapter for optic disc imaging.
Conjunctival UV autofluorescence (CUVAF) photography finds that, although a large environmental component to CUVAF exists, the genetic component also plays a significant role.
Results of a cytomegalovirus (CMV) retinitis telemedicine screening program instituted at a clinic for human immunodeficiency virus care determines that retinal photography may be used to identify disease with an immediate threat to vision.
This cross-sectional study conducted in the community setting reports identification of diabetic retinopathy on screening in approximately 1 in 5 persons with diabetes.
Joseph et al report a case of bilateral diffuse uveal melanocytic proliferation with multiple iris and ciliary body cysts in a woman with a history of clear cell adenocarcinoma of the endometrium.
To examine how mydriasis and the medical qualifications of photographers who take retinal photographs influence the accuracy of screening for diabetic retinopathy (DR).
Our meta-analysis included studies that measured the sensitivity and specificity of tests designed to detect any DR, sight-threatening DR, or macular edema. Using random-effects logistic regression, we examined the effect of variations in mydriatic status and in medical qualifications of photographers on sensitivity and specificity.
Only the category of “any DR” had sufficient consistency in definition, number of studies (n = 20), and number of assessments (n = 40) for meta-analysis. Variations in mydriatic status did not significantly influence sensitivity (odds ratio [OR], 0.89; 95% confidence interval [CI], 0.56-1.41; P = .61) or specificity (OR, 0.94; 95% CI, 0.57-1.54; P = .80). Variations in medical qualifications of photographers did not significantly influence sensitivity (OR, 1.25; 95% CI, 0.31-5.12; P = .75). Specificity of detection of any DR was significantly higher for screening methods that use a photographer with specialist medical or eye qualifications (OR, 3.86; 95% CI, 1.78-8.37; P = .001).
Outreach screening is an effective alternative to on-site specialist examination. It has potential to increase screening coverage of high-risk patients with DR in remote and resource-poor settings without the risk of missing DR and the opportunity to prevent vision loss. Our analysis was confined to the presence or absence of DR. Future studies should use consistent DR classification schemes to facilitate further analysis.