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Invited Critique |

Minimal Transfusions:  Comment on “Surgical Outcomes and Transfusion of Minimal Amounts of Blood in the Operating Room”

John B. Holcomb, MD
Arch Surg. 2012;147(1):55-56. doi:10.1001/archsurg.2011.1417.
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Ferraris et al1 have shed light on an important yet infrequently discussed problem. They reviewed patients who were not hypotensive or bleeding to death and received only small amounts of PRBCs in the operating room. Ferraris and colleagues showed that transfusion of even minimal amounts of blood products increases mortality, wound problems, pulmonary complications, postoperative renal dysfunction, systemic sepsis, composite morbidity, and postoperative length of stay. These are important outcomes that clinicians discuss every day.

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