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Original Article |

Association of Postdischarge Complications With Reoperation and Mortality in General Surgery

Hadiza S. Kazaure, MD; Sanziana A. Roman, MD; Julie A. Sosa, MD, MA
Arch Surg. 2012;147(11):1000-1007. doi:10.1001/2013.jamasurg.114.
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Objectives  To describe procedure-specific types, rates, and risk factors for postdischarge (PD) complications occurring within 30 days after 21 groups of inpatient general surgery procedures.

Design  Retrospective cohort study.

Setting  American College of Surgeons National Surgical Quality Improvement Program 2005 through 2010 Participant Use Data Files.

Patients  A total of 551 510 adult patients who underwent one of 21 groups of general surgery procedures in the inpatient setting.

Main Outcome Measures  Postdischarge complications, reoperation, and mortality.

Results  Of 551 510 patients (mean age, 54.6 years), 16.7% experienced a complication; 41.5% occurred PD. Of the PD complications, 75.0% occurred within 14 days PD. Proctectomy (14.5%), enteric fistula repair (12.6%), and pancreatic procedures (11.4%) had the highest PD complication rates. Breast, bariatric, and ventral hernia repair procedures had the highest proportions of complications that occurred PD (78.7%, 69.4%, and 62.0%, respectively). For all procedures, surgical site complications, infections, and thromboembolic events were the most common. Occurrence of an inpatient complication increased the likelihood of a PD complication (12.5% vs 6.2% without an inpatient complication; P < .001). Compared with patients without a PD complication, those with a PD complication had higher rates of reoperation (4.6% vs 17.9%, respectively; P < .001) and death (2.0% vs 6.9%, respectively; P < .001) within 30 days after surgery; those whose PD complication was preceded by an inpatient complication had the highest rates of reoperation (33.7%) and death (24.7%) (all P < .001). After adjustment, PD complications were associated with procedure type, American Society of Anesthesiologists class higher than 3, and steroid use.

Conclusions  The PD complication rates vary by procedure, are commonly surgical site related, and are associated with mortality. Fastidious, procedure-specific patient triage at discharge as well as expedited patient follow-up could improve PD outcomes.

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Figure 1. Frequency of postdischarge (PD) complications among general surgery patients who underwent inpatient procedures according to the American College of Surgeons National Surgical Quality Improvement Program 2005 through 2010 Participant Use Data Files.

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Figure 2. Predischarge vs postdischarge rates of complications among patients who underwent inpatient general surgery procedures according to the American College of Surgeons National Surgical Quality Improvement Program 2005 through 2010 Participant Use Data Files. DVT indicates deep venous thrombosis.

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Figure 3. Reoperation and mortality rates stratified by occurrence of a postdischarge (PD) complication according to the American College of Surgeons National Surgical Quality Improvement Program 2005 through 2010 Participant Use Data Files. The mortality rate among patients who experienced inpatient but not PD complications was 12.6%.

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Figure 4. Multivariate analysis of factors independently associated with occurrence of a postdischarge complication according to the American College of Surgeons National Surgical Quality Improvement Program 2005 through 2010 Participant Use Data Files. The multivariate model adjusted for more than 20 risk factors. The reference groups were American Society of Anesthesiologists (ASA) class lower than 3; operative wound classification of clean; procedure type of appendectomy; and, for all other references, no or not present. Error bars indicate 95% CIs.

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