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Original Article |

Outcomes and Predictors of Incisional Surgical Site Infection in Stoma Reversal

Mike K. Liang, MD; Linda T. Li, MD; Andres Avellaneda, MD; Jennifer M. Moffett, MD; Stephanie C. Hicks, MS; Samir S. Awad, MD
JAMA Surg. 2013;148(2):183-189. doi:10.1001/jamasurgery.2013.411.
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Importance  Surgical site infection following stoma reversal (SR) poses a substantial burden to the patient and health care system. Its overall incidence is likely underreported and poorly characterized. Improving our understanding of surgical site infection following stoma reversal may help us identify methods to decrease this complication.

Objective  To evaluate the incidence of surgical site infection (SSI) and identify predictors of SSI following SR.

Design  A review of computerized hospital records on SR performed from January 1, 2005, until February 27, 2011.

Setting  An integrated medical system at the Michael E. DeBakey Veterans Affairs Medical Center.

Participants and Intervention  All adults undergoing SR during the study period.

Main Outcome Measures  Rates of SSI and characteristics of patients with and without SSI were compared. A logistic regression model was developed to identify predictors of SSI.

Results  One hundred twenty-eight patients underwent SR; 46 patients (36.0%) had an SSI. In comparison with no SSI, the infection was associated with seromas (17.4% vs 2.4%, P = .004), fascial dehiscence (15.2% vs 2.4%, P = .01), intensive care unit admission (34.8% vs 17.1%, P = .03), increased hospital length of stay (20 vs 9 days, P = .02), readmission (32.6% vs 13.4%, P = .01), delayed wound healing (91 vs 66 days, P = .02), and reoperation (32.6% vs 13.4%, P = .01). On multivariate analysis, history of fascial dehiscence (odds ratio, 16.9; 95% CI, 1.94-387), colostomy (5.07; 2.12-13.0), thicker subcutaneous fat (2.02; 1.33-3.21), and black race (0.35; 0.13-0.86) were associated with incisional SSI. There was no significant difference in patient satisfaction or functional status in late follow-up (1-73 months).

Conclusions and Relevance  Surgical site infection is common following SR and is associated with significant morbidity. Four factors are strongly associated with increased risk of SSI in SR: history of fascial dehiscence, thicker subcutaneous fat, colostomy, and white race. Patients with none of these risk factors had a 0% SSI risk; patients with all 4 risk factors had a 100% risk of SSI.

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Figures

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Grahic Jump Location

Figure 1. Incidence of surgical site infection (SSI). *Of all the patients, 80 had a midline incision.

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Grahic Jump Location

Figure 2. Microbiologic results of surgical site infection (SSI) with stoma reversal.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

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