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SECTION EDITOR: CARL E. BREDENBERG, MD

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JAMA Surg. 2013;148(6):574-575. doi:10.1001/jamasurg.2013.304b.
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The computed tomographic scan findings were consistent with an incarcerated right inguinal hernia with acute appendicitis in the hernia sac. A laparoscopic appendectomy was performed, an inflamed internal ring was found, and a temporary repair was performed by dissecting and suturing a portion of the adjacent lateral vesicoumbilical ligament to the internal inguinal ring (Figure 3).

Place holder to copy figure label and caption
Graphic Jump Location

Figure 3. Temporary repair of hernia.

A 1-cm T1a appendiceal carcinoid tumor was found. The patient returned to the operating room 6 weeks later for exploratory laparoscopy; no additional evidence of malignancy was found, and the primary hernia repair was adequate. He underwent a formal transabdominal preperitoneal repair with mesh, and his recuperation was uneventful.

An inguinal hernia is termed an Amyand hernia if the hernia sac comprises or contains the appendix. To our knowledge, the presence of an appendiceal carcinoid tumor presenting as a case of incarcerated Amyand hernia has not been reported in the literature. We report the first case of this unusual presentation.

Amyand hernia has frequently been reported in younger (>2 years) and older (>60 years) individuals.1,2 A preoperative diagnosis is rare; more often, the diagnosis is made during surgery.3 Amyand hernia may mimic entirely different disease processes; therefore, a high index of suspicion is warranted. In the literature, the clinical presentations vary greatly: from the most common right-sided hernia,2,4,5 to a left-sided hernia,6 an incarcerated inguinal hernia, testicular torsion,7,8 to the extremes of necrotizing fasciitis and shock.9,10 The contents of a hernia can be a normal-appearing, an inflamed, or a perforated appendix. Malignancy is extremely rare, with only 2 case reports of adenocarcinoma of the appendix.11,12 To the best of our knowledge, this is the first case of the presence of an appendiceal carcinoid tumor in an Amyand hernia. Appendiceal carcinoids comprise 1% of all appendectomy specimens, and the size, extension, histology, and mitotic activity of the tumor are useful predictors of malignancy.

The diagnosis of Amyand hernia is usually obtained intraoperatively. However, the diagnosis has been achieved preoperatively using ultrasonography13 and computed tomography.14,15 In this case, a radiographic diagnosis was made preoperatively with a computed tomographic scan and was confirmed during surgery.

The management of a Amyand hernia varies depending on the presence or absence of appendiceal inflammation; if, during an exploration, the appendix appears benign, some have advocated against an appendectomy.16 However, if the patient is in the operating room and the diagnosis has been made, it is prudent to remove the appendix, regardless of its gross appearance, the possibility of misdiagnosis, or the possibility of it not being malignant. The timing and approach (open or laparoscopic) of the repair,17 with or without placement of mesh,18 are common subjects of debate.

We believe that the decision should be made on a case-by-case basis. A total extraperitoneal repair has also been reported.19 This approach carries the disadvantage of not visualizing the appendix directly and, thus, the subsequent inability to address a pathologic appendix.

In our case, we selected a laparoscopic transabdominal preperitoneal approach, for both the appendectomy and the primary hernia repair; this approach allowed us to minimize tissue trauma by avoiding the conventional McBurney incision and its possible subsequent morbidity. In addition, the laparoscopic approach allowed us to reexplore the area with minimal adhesion formation and adequate visualization of the entire abdominal cavity.

The choice of using the adjacent lateral vesicoumbilical ligament as an autologous biomaterial for the temporary repair was an inexpensive and innovative solution that, in the presence of contamination, proved to be an adequate solution. We believe that it is sometimes warranted to defer the definitive repair of the hernia, and, in this case, deferring the definitive repair proved useful by providing the patient with adequate time to decrease the bacterial load at the hernia site while allowing for the final pathology report to arrive and thus help us formulate a reoperative strategy that included a complete laparoscopic exploration in addition to the formal repair of the inguinal hernia in a noncontaminated area.

Return to Quiz Case.

Correspondence: Nissin C. Nahmias, MD, Department of Surgery, University of Connecticut School of Medicine, St Francis Hospital and Medical Center, 1000 Asylum Ave, Ste 432, Hartford, CT 06105 (nnahmias@stfranciscare.org).

Accepted for Publication: March 10, 2012.

Author Contributions:Study concept and design: All authors. Acquisition of data: Nahmias and Muddasani. Analysis and interpretation of data: All authors. Drafting of the manuscript: All authors. Critical revision of the manuscript for important intellectual content: Nahmias. Administrative, technical, and material support: Nahmias. Study supervision: Nahmias.

Conflict of Interest Disclosures: None reported.

Cankorkmaz L, Ozer H, Guney C, Atalar MH, Arslan MS, Koyluoglu G. Amyand's hernia in the children: a single center experience.  Surgery. 2010;147(1):140-143
PubMed   |  Link to Article
Rehman MR, Panteli C, Tsang T. Laparoscopic repair of Amyand's hernia in an 8-week-old infant.  Hernia. 2010;14(4):443-445
PubMed   |  Link to Article
Inan I, Myers PO, Hagen ME, Gonzalez M, Morel P. Amyand's hernia: 10 years' experience.  Surgeon. 2009;7(4):198-202
PubMed   |  Link to Article
Agko M, Castillo-Sang M, Tsang AW, Cason FD. Amyand's hernia: an unusual appendix within an inguinal hernia.  Am Surg. 2010;76(11):1314-1315
PubMed
Doyle GS, McCowan C. Amyand hernia: a case of an unusual inguinal herniace.  Am J Emerg Med. 2008;26(5):637.e5-637.e6
PubMed   |  Link to Article
Malik KA.  Left sided Amyand's hernia.  J Coll Physicians Surg Pak. 2010;20(7):480-481
PubMed
Kumar R, Mahajan JK, Rao KL. Perforated appendix in hernial sac mimicking torsion of undescended testis in a neonate.  J Pediatr Surg. 2008;43(4):e9-e10
PubMed   |  Link to Article
Milburn JA, Youngson GG. Amyand's hernia presenting as neonatal testicular ischaemia.  Pediatr Surg Int. 2006;22(4):390-392
PubMed   |  Link to Article
Bhide SS. Amyand's hernia.  Indian J Pediatr. 2009;76(8):854-855
PubMed   |  Link to Article
Marron CD, Khadim M, McKay D, Mackle EJ, Peyton JW. Amyand's hernia causing necrotising fasciitis of the anterior abdominal wall.  Hernia. 2005;9(4):381-383
PubMed   |  Link to Article
Wu CL, Yu CC. Amyand's hernia with adenocarcinoid tumor.  Hernia. 2010;14(4):423-425
PubMed   |  Link to Article
Rezkalla MA, Peterson KG, Ryan JJ. Pseudomyxoma peritonei: a case of mucinous adenocarcinoma of the appendix presenting as inguinal hernia.  S D Med. 2006;59(2):54-55, 57
PubMed
Coulier B, Pacary J, Broze B. Sonographic diagnosis of appendicitis within a right inguinal hernia (Amyand's hernia).  J Clin Ultrasound. 2006;34(9):454-457
PubMed   |  Link to Article
Maizlin ZV, Mason AC, Brown C, Brown JA. CT findings of normal and inflamed appendix in groin hernia.  Emerg Radiol. 2007;14(2):97-100
PubMed   |  Link to Article
Meinke AK. Review article: appendicitis in groin hernias.  J Gastrointest Surg. 2007;11(10):1368-1372
PubMed   |  Link to Article
Sharma H, Gupta A, Shekhawat NS, Memon B, Memon MA. Amyand's hernia: a report of 18 consecutive patients over a 15-year period.  Hernia. 2007;11(1):31-35
PubMed   |  Link to Article
Milanchi S, Allins AD. Amyand's hernia: history, imaging, and management.  Hernia. 2008;12(3):321-322
PubMed   |  Link to Article
Chatzimavroudis G, Papaziogas B, Koutelidakis I,  et al.  The role of prosthetic repair in the treatment of an incarcerated recurrent inguinal hernia with acute appendicitis (inflamed Amyand's hernia).  Hernia. 2009;13(3):335-336; author reply 337
PubMed   |  Link to Article
Sarker SK, Jackson K. Laparoscopic extraperitoneal repair of Amyand's inguinal hernia.  JSLS. 2006;10(4):528-530
PubMed

Figures

Place holder to copy figure label and caption
Graphic Jump Location

Figure 3. Temporary repair of hernia.

Tables

References

Cankorkmaz L, Ozer H, Guney C, Atalar MH, Arslan MS, Koyluoglu G. Amyand's hernia in the children: a single center experience.  Surgery. 2010;147(1):140-143
PubMed   |  Link to Article
Rehman MR, Panteli C, Tsang T. Laparoscopic repair of Amyand's hernia in an 8-week-old infant.  Hernia. 2010;14(4):443-445
PubMed   |  Link to Article
Inan I, Myers PO, Hagen ME, Gonzalez M, Morel P. Amyand's hernia: 10 years' experience.  Surgeon. 2009;7(4):198-202
PubMed   |  Link to Article
Agko M, Castillo-Sang M, Tsang AW, Cason FD. Amyand's hernia: an unusual appendix within an inguinal hernia.  Am Surg. 2010;76(11):1314-1315
PubMed
Doyle GS, McCowan C. Amyand hernia: a case of an unusual inguinal herniace.  Am J Emerg Med. 2008;26(5):637.e5-637.e6
PubMed   |  Link to Article
Malik KA.  Left sided Amyand's hernia.  J Coll Physicians Surg Pak. 2010;20(7):480-481
PubMed
Kumar R, Mahajan JK, Rao KL. Perforated appendix in hernial sac mimicking torsion of undescended testis in a neonate.  J Pediatr Surg. 2008;43(4):e9-e10
PubMed   |  Link to Article
Milburn JA, Youngson GG. Amyand's hernia presenting as neonatal testicular ischaemia.  Pediatr Surg Int. 2006;22(4):390-392
PubMed   |  Link to Article
Bhide SS. Amyand's hernia.  Indian J Pediatr. 2009;76(8):854-855
PubMed   |  Link to Article
Marron CD, Khadim M, McKay D, Mackle EJ, Peyton JW. Amyand's hernia causing necrotising fasciitis of the anterior abdominal wall.  Hernia. 2005;9(4):381-383
PubMed   |  Link to Article
Wu CL, Yu CC. Amyand's hernia with adenocarcinoid tumor.  Hernia. 2010;14(4):423-425
PubMed   |  Link to Article
Rezkalla MA, Peterson KG, Ryan JJ. Pseudomyxoma peritonei: a case of mucinous adenocarcinoma of the appendix presenting as inguinal hernia.  S D Med. 2006;59(2):54-55, 57
PubMed
Coulier B, Pacary J, Broze B. Sonographic diagnosis of appendicitis within a right inguinal hernia (Amyand's hernia).  J Clin Ultrasound. 2006;34(9):454-457
PubMed   |  Link to Article
Maizlin ZV, Mason AC, Brown C, Brown JA. CT findings of normal and inflamed appendix in groin hernia.  Emerg Radiol. 2007;14(2):97-100
PubMed   |  Link to Article
Meinke AK. Review article: appendicitis in groin hernias.  J Gastrointest Surg. 2007;11(10):1368-1372
PubMed   |  Link to Article
Sharma H, Gupta A, Shekhawat NS, Memon B, Memon MA. Amyand's hernia: a report of 18 consecutive patients over a 15-year period.  Hernia. 2007;11(1):31-35
PubMed   |  Link to Article
Milanchi S, Allins AD. Amyand's hernia: history, imaging, and management.  Hernia. 2008;12(3):321-322
PubMed   |  Link to Article
Chatzimavroudis G, Papaziogas B, Koutelidakis I,  et al.  The role of prosthetic repair in the treatment of an incarcerated recurrent inguinal hernia with acute appendicitis (inflamed Amyand's hernia).  Hernia. 2009;13(3):335-336; author reply 337
PubMed   |  Link to Article
Sarker SK, Jackson K. Laparoscopic extraperitoneal repair of Amyand's inguinal hernia.  JSLS. 2006;10(4):528-530
PubMed

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