During the 19th century, Spanish surgery began to acquire scientific principles and to experience major advances, mainly due to new breakthroughs in the use of anesthesia, asepsis, antisepsis, and other technical improvements. The emergence of scientific publications and visits by Spanish surgeons to hospitals and institutions throughout all of Europe encouraged the exchange of knowledge and facilitated the standardization of criteria. The work of leading European surgeons such as Dupuytren, Roux, Pean, Hartmann, Delorme, Quenu, Billroth, Kocher, and Lister deeply influenced the technical and scientific development of Spanish surgery. Many surgeons, usually in possession of thorough anatomical training, practiced new operations on cadavers. New techniques described abroad were swiftly incorporated into clinical practice; in fact, Rubió performed axillary node dissection for breast cancer before Kocher and Halsted.1