0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Comment & Response |

Less Surgery, Improved Survival From Stage IV Colorectal Cancer?—Reply

Chung-Yuan Hu, MPH, PhD1; Christina E. Bailey, MD, MS1; George J. Chang, MD, MS1,2
[+] Author Affiliations
1Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston
2Department of Health Services Research, University of Texas MD Anderson Cancer Center, Houston
JAMA Surg. 2015;150(8):819-820. doi:10.1001/jamasurg.2015.0683.
Text Size: A A A
Published online

Extract

In Reply In our recent study entitled “Time Trend Analysis of Primary Tumor Resection for Stage IV Colorectal Cancer: Less Surgery, Improved Survival,”1 we noted a trend toward improved survival despite decreasing primary tumor resection (PTR) rates for patients presenting with unresectable metastatic colorectal cancer (MCRC). We observed improvements in survival that coincided with the availability of new systemic treatment options. However, more than 50% of patients who present with MCRC are still undergoing PTR. Based on these results, we concluded that PTR may be overused among patients with MCRC. As noted by Price and colleagues, to date, little is known about the effect of PTR on survival. Although multiple retrospective studies have associated PTR with a survival benefit, these studies are subject to the strong confounding effects of treatment selection, and survivor time biases limit the interpretation of their findings (eg, patients undergoing PTR may be less likely than patients not undergoing PTR to have an advanced disease burden or comorbid conditions).

Topics

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

August 1, 2015
Timothy J. Price, MBBS, FRACP, DHSc; Niall Tebbutt, MBBS, FRACP, PhD; Amanda R. Townsend, MBBS, FRACP
1The Queen Elizabeth Hospital and University of Adelaide, Woodville, South Australia, Australia
2Olivia Newton-John Cancer and Wellness Centre, Austin Health, Melbourne, Victoria, Australia.
JAMA Surg. 2015;150(8):818. doi:10.1001/jamasurg.2015.0680.
August 1, 2015
Rachel Wong, MBBS(Hons), FRACP; Peter Gibbs, MBBS, FRACP, MD
1Department of Medical Oncology, Eastern Health, Monash University, Box Hill, Victoria, Australia
2Walter and Eliza Hall Institute of Medical Research, Department of Medical Oncology, Royal Melbourne and Western Hospitals, Parkville, Melbourne, Victoria, Australia
JAMA Surg. 2015;150(8):818-819. doi:10.1001/jamasurg.2015.1331.
CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

188 Views
0 Citations
×

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...
Jobs
brightcove.createExperiences();