Selected clinicopathologic characteristics of locally treated rectal cancers are predictive of recurrence.
Case series review with median follow-up of 6 years.
University medical center.
Fifty-eight patients with rectal cancer who underwent local excisions from February 1, 1982, to December 31, 1998.
Main Outcome Measures
Local and distant recurrence rates and overall survival.
Overall local recurrence rate was 14% (8 patients). There were no local recurrences among patients treated with chemotherapy or radiation. Of patients not treated, local recurrence rates were 33%, 5%, 45%, and 25% for T0, T1, T2, and T3 tumors, respectively. No clinicopathologic factor predicted local recurrence. Two patients developed distant recurrence. Overall survival was 98%, 93%, and 84% at 1, 3, and 5 years, respectively.
In selected patients, outcomes for local excision combined with additional therapy may be equivalent to those for radical resection.