A 34-year-old woman was admitted with abdominal pain predominantly at the right side and rectal bleeding of several days' duration. She had been diagnosed as having Gardner syndrome 2 years before. Among the manifestations of this disease were multiple osteomas and polyposis coli, for which a subtotal colectomy and ileorectal anastomosis had been performed. Physical examination findings revealed fullness of the abdomen with a nonmobile mass measuring approximately 30 cm in diameter. No source for the rectal bleeding could be detected at rectoscopy. Ultrasonography showed a very large, solid intra-abdominal tumor, which was confirmed by computed tomographic scanning. The tumor, measuring 23 × 15 cm, extended onto the left liver lobe and could not be distinguished from the abdominal wall (Figure 1). To obtain histologic characteristics, the abdomen was opened through a left pararectal incision. Immediately, it became clear that there was tumor infiltration into the left rectus muscle. A large biopsy specimen of this tissue was taken, as well as incisional biopsy specimens of tumor infiltrating the mesentery (Figure 2). The tumor was considered unresectable because of diffuse large- and small-bowel mesenteric invasion. The patient is currently being treated with tamoxifen citrate, 40 mg/d, and was responding well at this report, 7 months after the operation.
A.Gastrointestinal stromal tumor B.Fibrosarcoma C.Desmoid tumor D.Ovarian carcinoma
Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature
Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal
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