Fluorescent IOC with intravenous ICG injection has potential advantages over radiographic IOC. First, the technique we described can save time and avoid bile duct injury associated with the insertion of a transcystic tube.2 Second, it is convenient. Using only a preoperative intravenous ICG injection, surgeons can obtain fluorescent images of the biliary tract at any time, without radiation technicians. Third, fluorescent imaging enables the distinct identification of the biliary tract in relation to surrounding structures and organs, though its ability to detect common bile duct stones remains unclear. Lastly, fluorescent IOC is safe. It does not require irradiation, and the risk related to the administration of ICG is quite small (approximately 0.003% at doses in excess of 0.5 mg/kg).6 With further refinements in image resolution, fluorescent IOC may become the optimal tool to confirm biliary tract anatomy for safer laparoscopic cholecystectomy.