A 54-year-old woman presented with chronic intermittent sharp midepigastric abdominal pain. She denied having jaundice or a change in her bowel function but admitted to a 5.4-kg weight loss over 3 months. Medical, surgical, family, and social histories were unremarkable. There was no history of neurofibromatosis 1. The results of physical examination and routine laboratory tests, including liver function tests, were normal. A right upper quadrant ultrasonographic and computed tomographic (CT) scan with contrast revealed a 1.4-cm enhancing lesion in the head of the pancreas without duct dilation (Figure 1).