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Arch Surg. 2011;146(2):236. doi:10.1001/archsurg.2010.341-b.
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Appendix invertus, a surgically inverted appendix, is a result of a type of appendicectomy, where the appendix is inverted into the cecum. Historically, some surgeons used the technique of inversion-ligation appendectomy to theoretically reduce the risk of peritoneal contamination in the setting of acute appendicitis.14 This technique has also been used for incidental appendectomy performed during laparotomy for unrelated problems. The resultant appendiceal stump usually necroses and sloughs into the colonic lumen after several days, but remnant tissue may persist in some patients. Currently, the inversion-ligation technique is rarely used during an open or laparoscopic procedure. Many adults currently presenting for screening colonoscopy have undergone appendectomy decades earlier when this procedure was common practice. It is likely that our patient underwent appendectomy using the inversion-ligation technique; however, we were unable to confirm it because of the lack of an available operative record.

Inverted appendix does not cause any symptoms but may cause differential diagnostic problems when examining pictures from a large-bowel radiography examination or on colonoscopy.5 Sometimes the appendicular stump resembles a polyp at the appendiceal orifice in patients postappendectomy, usually with purse-string suture. The most common appearance of the inverted appendiceal stump consists of a raised prominence at the cecal tip. In less prominent cases, correlating this finding with the patient's history of appendectomy allows confident diagnosis. The postoperative appearance at the appendiceal orifice, however, can be quite variable. The appendiceal stump may be enlarged by postoperative hemorrhage or by stump appendicitis. The entire cecal tip may also become flattened as a result of surgery in this area.

Other than resulting from surgery, an inverted appendix can be congenital or due to an intussusception associated with diseases such as appendix tumors, mucocele, fecalith, or worms. Our patient was asymptomatic, suggesting intussusception as an unlikely cause. In our patient, an attempt was made to reduce the appendix but was unsuccessful, likely because of the ligation after inversion. High-resolution narrow-band imaging is a technologically advanced method of endoscopic imaging that can help differentiate neoplastic and non-neoplastic lesions by revealing their characteristic surface vascular pattern.6 It showed normal mucosa in our patient and thus excluded mucosa-based neoplasm. Additionally, the characteristic location and endoscopic appearance of the lesion and the surgical history of the patient were considered to be most compatible with an inverted appendiceal stump. No further therapeutic intervention is necessary when the diagnosis is convincing.

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Correspondence: Sushil Ahlawat, MD, University Hospital, Ste E-178, 150 Bergen St, Newark, NJ 07103 (sushilka@aol.com).

Accepted for Publication: November 13, 2009.

Author Contributions:Study concept and design: Ahlawat. Acquisition of data: Kaswala, Patel, and Ahlawat. Analysis and interpretation of data: Ahlawat. Drafting of the manuscript: Kaswala, Patel, and Ahlawat. Critical revision of the manuscript for important intellectual content: Ahlawat. Statistical analysis: Ahlawat. Obtained funding: Ahlawat. Administrative, technical, and material support: Kaswala, Patel, and Ahlawat. Study supervision: Ahlawat.

Financial Disclosure: None reported.

Engström  LFenyö  G Appendicectomy: assessment of stump invagination versus simple ligation. a prospective, randomized trial. Br J Surg 1985;72 (12) 971- 972
PubMed
Järvensivu  PLehtola  JKarvonen  ALRinne  ASuramo  I Colonoscopic appearance of the remnant of the appendix after total inversion. Endoscopy 1982;14 (2) 66- 68
PubMed
Myllärniemi  HPerttala  YPeltokallio  P Tumor-like lesions of the cecum following inversion of the appendix. Am J Dig Dis 1974;19 (6) 547- 556
PubMed
Vaughn  AMWidran  J Inverted appendical stump simulating cancer of the cecum. J Am Med Assoc 1954;154 (12) 996- 997
PubMed
Pickhardt  PJ Differential diagnosis of polypoid lesions seen at CT colonography (virtual colonoscopy). Radiographics 2004;24 (6) 1535- 1559
PubMed
Larghi  ALecca  PGCostamagna  G High-resolution narrow band imaging endoscopy. Gut 2008;57 (7) 976- 986
PubMed

Figures

Tables

References

Engström  LFenyö  G Appendicectomy: assessment of stump invagination versus simple ligation. a prospective, randomized trial. Br J Surg 1985;72 (12) 971- 972
PubMed
Järvensivu  PLehtola  JKarvonen  ALRinne  ASuramo  I Colonoscopic appearance of the remnant of the appendix after total inversion. Endoscopy 1982;14 (2) 66- 68
PubMed
Myllärniemi  HPerttala  YPeltokallio  P Tumor-like lesions of the cecum following inversion of the appendix. Am J Dig Dis 1974;19 (6) 547- 556
PubMed
Vaughn  AMWidran  J Inverted appendical stump simulating cancer of the cecum. J Am Med Assoc 1954;154 (12) 996- 997
PubMed
Pickhardt  PJ Differential diagnosis of polypoid lesions seen at CT colonography (virtual colonoscopy). Radiographics 2004;24 (6) 1535- 1559
PubMed
Larghi  ALecca  PGCostamagna  G High-resolution narrow band imaging endoscopy. Gut 2008;57 (7) 976- 986
PubMed

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