Invited Critique |

Morbidity in Live Liver Donors—Invited Critique

Susan L. Orloff, MD
Arch Surg. 2005;140(9):896. doi:10.1001/archsurg.140.9.896.
Text Size: A A A
Published online


This article reports on a retrospective review of AE among live liver donors in a university-affiliated teaching hospital. Thirty-four patients underwent right lobectomy while 3 had a left-lateral segmentectomy. Any event causing a deviation from a patient’s ideal course was considered an AE, and the incidence, timing, type, severity, and impact of AEs were studied. The purpose of the current report is first, to review, analyze, and report morbid events related to the live liver donor process in a consecutive series from the authors’ center, and second, to apply a further derivation of an AE classification framework to provide an additional step toward the development of standards-based morbidity reporting. Shackleton et al found no deaths or significant hepatic dysfunction in the live donor patients. In 5 (11.9%) of 42 patients, the hepatectomy was aborted for anatomic reasons prior to proceeding with the liver resection. Eight (21.6%) of the remaining 37 experienced 11 AEs, of which 10 completely resolved. The overall incidence of AEs was 0.3 per case. The authors conclude that (1) the majority of live liver donations are either uncomplicated or do not lead to permanent consequence, and (2) the adoption of a standards-based classification framework for AEs in live liver donors should allow for an inclusive, consistent, and universally applicable method to collect, analyze, and report donor morbidity.

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
First page PDF preview





Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...
Articles Related By Topic
Related Topics
PubMed Articles