I read with great interest the article by Yang et al1 about the effect of core-needle biopsy (CNB) and fine-needle aspiration (FNA) on the measurement of tumor size in breast cancer. The authors claim that alteration of the tumor size after CNB and FNA will alter the treatment regimen. This is an interesting study that has not been done in the past in such detail.
But the important question remains how the change in size of the tumor after CNB and FNB affects the management of the patient.
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