In a previous article1 the results of an experimental study to determine the routes by which infection could ascend from the bladder and involve the upper urinary tract were published. In that article these statements were made:
In experimental B. coli cystitis in dogs, blood stream infection rarely takes place.
Without stasis of urine, involvement of the upper urinary tract is rare.
With slight obstruction to complete emptying of the bladder, extension of infection to the upper urinary tract practically always occurs.
The involvement of the upper urinary tract almost uniformly takes place through the lumen of the ureter, and the ureteral lymphatics are rarely, if ever, the pathway of infection.
Since some of these statements are at variance with the reports of other workers on the same, or correlated, subjects, further evidence will be presented bearing on the rôle of the ureteral lymphatics as