There have been a few experimental and clinical studies that have suggested the possible occurrence of a selective distribution of portal blood in the liver and the presence of independent currents of blood in the portal vein. Final proof of the presence of these currents has not been established, and the selective distribution of portal blood in the liver has been held in doubt. The possible existence of segregated streams of blood in the portal vein and their subsequent distribution to definite parts of the liver is of interest and should be of considerable practical significance in the study of the physiology and pathology of the liver. The evidence in favor of the existence of these phenomena has not generally been known or seemingly accepted.
In 1901, Sérégé1 injected india ink into the splenic vein of the dog and found particles only in the left lobe of the liver;