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Arch Surg. 1930;20(3):421-436. doi:10.1001/archsurg.1930.01150090068003.
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INTRODUCTION  From among the reports of cases of malignant tumors of the bone in the Surgical Pathological Laboratory of the Johns Hopkins Hospital representing in all a total of more than 400 cases, a series of 60 cases which were grouped under the name of periosteal round cell sarcoma or Ewing's endothelial myeloma were selected for the present analysis.The result of this analysis has brought forth many interesting and novel features in the natural history and clinical course of this tumor,1 Under the direction of Dr. Bloodgood the cases were first studied microscopically and later correlated with clinical data, the prognosis and ultimate result being made available in fifty-two of these cases by clinical follow-ups.Ewing's sarcoma is essentially a disease of early life, the majority of the tumors occurring during the first two decades (95 per cent). The age incidence ranges between 4½ and 44 years. The


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