Owing to the frequent employment of spinal anesthesia in recent years, a clearer understanding of its effect on the general circulation seems important. Occasional deaths following its use have been unexplained. Recently, we had occasion to observe a patient who died following the termination of an operation under spinal anesthesia. During the operation approximately 250 cc. of blood was lost. As no other cause for the patient's death was found, it was believed that the hemorrhage probably was responsible for it. The loss of this amount of blood in an adult patient under ether anesthesia does not usually produce deleterious effects.
The purpose of the present study is to determine the effects of loss of blood under ether anesthesia and under spinal anesthesia.
Dogs were used in all experiments. The blood pressure level was determined by placing in the carotid artery a cannula which was connected to a mercury