Arch Surg. 1932;24(6):990-1015. doi:10.1001/archsurg.1932.01160180100005.
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In the management of ununited fractures, as with all other injuries and diseases of bones, one is dealing with a problem about which there is, generally speaking, not the slightest conception. Bone is usually regarded as an inert substance the function of which is purely mechanical, whereas bone in fact is a most active living tissue and just as vital and essential to life as any organ in the body. In addition to acting as a mechanical support to the body through the skeletal system, bone is the storehouse of calcium, which is just as necessary to the well being of the organism as glycogen of the liver. Also, encased within the bone is the marrow from which the blood, the vital fluid of life, is largely manufactured. Throughout the bone is an orderly system of blood vessels, nerves and lymphatics which supply elements essential to a living tissue and


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