Arch Surg. 1933;27(1):51-62. doi:10.1001/archsurg.1933.01170070054002.
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Secondary anemia following excessive uterine hemorrhage constitutes a frequent and important complication of gynecologic disorders. When the bleeding is the result of such gross lesions as uterine fibroids, a severe degree of anemia may present a situation requiring considerable delicacy of judgment in its handling. A major surgical procedure is usually necessary to stop the excessive flow effectively and permanently, and before the surgeon is justified in operating the anemia must be effectively treated to an extent sufficient to render the procedure a safe risk; this must usually be accomplished in the all too brief interval between two prolonged and profuse menstrual periods. It is therefore essential that one have at one's disposal efficient and speedy methods of effecting such an improvement.

For many years iron in one form or another has been the standard drug used in the treatment of such conditions, and more recently transfusion has proved to


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