A number of soldiers were brought to the Chinese Red Cross General Hospital with wounds of the head sustained in the recent Sino-Japanese hostilities at Shanghai. All these wounds were infected. During the first few weeks of this period the outcome in each case seemed to be determined by the course of the infection. The wounds were treated in a routine manner by irrigation and dressings with surgical solution of chlorinated soda. During the last few weeks bacterial filtrates were used instead of the solution as a further means of controlling the infection. Eight of the last ten patients admitted with open infected wounds of the head involving the brain received treatment with filtrates. We herewith report the results of this treatment.
Smears and cultures were made from the wounds as soon as possible after the admission of the patients to the neurosurgical division. The surgical condition was then