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PATHOGENESIS OF ACUTE PANCREATITIS (ACUTE PANCREATIC NECROSIS)

LESTER R. DRAGSTEDT, Ph.D., M.D.; H. E. HAYMOND, M.D.; JAMES C. ELLIS, M.D.
Arch Surg. 1934;28(2):232-291. doi:10.1001/archsurg.1934.01170140012002.
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Introduction

Etiology of Acute Pancreatic Necrosis

Common Channel Theory and Objections to It

Relation of Bile to Acute Pancreatic Necrosis

Nonbiliary Causes of Acute Pancreatic Necrosis

Mechanism of Production of Acute Pancreatic Necrosis

Does Intraglandular Activation of Trypsin Cause Acute Pancreatic Necrosis?

Mechanism of Production of Acute Pancreatic Necrosis by Bile

Summary

Cause of Death in Acute Pancreatic Necrosis

Observations on the Toxicity of Pancreatic Juice

Intraperitoneal Injection of Fresh, Actively Proteolytic Pancreatic Juice

Intravenous Injection of Fresh, Actively Proteolytic Pancreatic Juice

Intraperitoneal Injection of Fresh, Actively Proteolytic Pancreatic Juice, Sterilized by Berkefeld Filtration

Intraperitoneal Injection of Fresh, Actively Proteolytic Pancreatic Juice from the Dog into Mice

Comment

Observations on the Toxicity of the End-Products of Pancreatic Digestion and Autolysis and the Rôle of Bacteria in the Toxemia of Acute Pancreatic Necrosis

In Vivo Autolysis of Dog Pancreas Complicated by the Presence of Bacteria Commonly Found in the Uncontaminated Gland

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