Arch Surg. 1934;28(5):920-935. doi:10.1001/archsurg.1934.01170170115009.
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The results of sympathetic ganglionectomy in the surgical treatment of disease in many cases strongly suggest that dysfunction of the autonomic nerves is a factor in the disease process in question. The basic causes of the autonomic dysfunction, however, are not as yet fully understood. Lesions of the autonomic ganglions and ganglion cells doubtless must be regarded as important factors in many cases, but our knowledge of these lesions and their functional significance is fragmentary and incomplete.

REVIEW OF THE LITERATURE  Most of the data available at present regarding lesions of the autonomic ganglions and ganglion cells represent the results of histopathologic studies of preparations of ganglions obtained at autopsy following death due to a wide variety of causes. The earlier studies of this character, the results of which have been published, have been reviewed by Stämmler1 (1923), who also reported the results of his own studies of ganglions


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