Since 1922, 43 patients have fulfilled the requirements for a diagnosis of Banti's syndrome at the State University Hospitals. Half of these patients were treated by splenectomy, and the remainder were treated conservatively. A comparison of the two groups was made in an effort to determine the effects of splenectomy.
This syndrome was separated from other splenic enlargements by Banti1 in 1883, 1894 and 1910 and is frequently spoken of as Banti's disease. In 1900, Osler2 reported a series of cases of a similar condition, which he called splenic anemia. The two terms are used interchangeably both in the United States and on the Continent. The English and German authors reserve the term Banti's disease for the advanced condition, with marked cirrhosis of the liver. American writers also include under the terms splenic anemia and Banti's disease splenomegaly with anemia caused by syphilis, tuberculosis and malaria.