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August 1940, Vol 41, No. 2 >
ARTICLE | August 1940

FEVER AS INITIAL SYMPTOM OF HYPERNEPHROID TUMOR OF THE KIDNEY

E. J. McCAGUE, M.D.
Arch Surg. 1940;41(2):385-392. doi:10.1001/archsurg.1940.01210020181018.
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The purpose of this brief paper is to report a case of renal tumor in which the classic triad of hematuria, pain and a palpable abdominal mass was absent. The only clinical manifestation was an obscure febrile state of one year's duration, accompanied with nausea, vomiting and irregular uterine bleeding from multiple fibroids.

FEVER WITH RENAL NEOPLASIA  The first reference to fever associated with renal neoplasia was made by Israel1 in 1896. In the case reported by him a man 43 years of age suffered from a hectic remittent fever for several months. At operation a right hypernephroid tumor of the kidney was found. The fever promptly disappeared after removal of the kidney.In 1911, Israel2 again commented on the importance of fever as a diagnostic symptom of renal tumor. It was present as part of the picture in 18.3 per cent of the cases that he reported.

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