0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

POSTOPERATIVE HYPOPROTHROMBINEMIA AND ANESTHESIA

J. GARROTT ALLEN, M.D.; H. LIVINGSTONE, M.D.
Arch Surg. 1941;42(3):522-528. doi:10.1001/archsurg.1941.01210090071005.
Text Size: A A A
Published online

It is generally agreed that a reduction of the prothrombin content of the plasma frequently is seen during the postoperative period in patients with biliary fistula or obstructive jaundice. Such a reduction may occur even though preoperative correction of any prothrombin deficiency has been carried out through the medium of vitamin K and bile salt therapy. The hypoprothrombinemia seen in some of these patients may be so severe as to give rise to brisk hemorrhage during the postoperative period.1

The cause of the postoperative prothrombin reduction seen in many patients with biliary fistula or obstructive jaundice has been subjected to controversy. In theory the postoperative hypoprothrombinemia may be the result of three factors: (1) loss of prothrombin commensurate with the amount of blood lost; (2) damage to the liver attendant on surgical procedures and anesthesia, and finally (3) failure to reestablish the body's normal reserves of prothrombin or one

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
/>
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();