0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

PHYSIOLOGIC EFFECTS OF HIGH CONCENTRATIONS OF OXYGEN IN EXPERIMENTAL SECONDARY SHOCK

HARRY A. DAVIS, M.D.
Arch Surg. 1941;43(1):1-13. doi:10.1001/archsurg.1941.01210130004001.
Text Size: A A A
Published online

Despite the widespread use of oxygen therapy for clinical shock, few studies have been made of the effect of high concentrations of oxygen in experimental shock. The rationale of the method is based on the fall of oxygen consumption associated with hemorrhagic and traumatic shock, which was first pointed out by Aub and Cunningham1 and which has since been confirmed by many other workers. The present report concerns a series of experiments undertaken to investigate the physiologic action of high concentrations of oxygen on normal control animals and experimental animals in which secondary shock had been produced.

MATERIALS AND METHODS  Dogs weighing from 10 to 25 pounds (4.5 to 11.3 Kg.) were kept under light anesthesia produced by intravenous injection of pentobarbital sodium in doses of 1/4 grain (0.015 Gm.) per kilogram of body weight. The arterial blood pressure was recorded with a mercury manometer by means of a

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();