We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |


Arch Surg. 1942;45(4):596-605. doi:10.1001/archsurg.1942.01220040092010.
Text Size: A A A
Published online


The fall in blood pressure which all observers agree is commonly found accompanying spinal anesthesia has been ascribed in the main to two causes: (1) dilatation of the arterioles in the anesthetized area due to a block of vasoconstrictor fibers in the anesthetized roots1; (2) decreased cardiac output.2

The evidence in the literature for diminished vasoconstriction is as follows:

Burch and Harrisonle showed that spinal anesthesia increases the rate of flow of perfusion fluid through the femoral and brachial arteries of dogs. They showed also that compensatory vasoconstriction following hemorrhage by bleeding as shown by a marked diminution in the perfusion rate does not occur in the animals which receive spinal anesthesia, since in these animals the perfusion rate is unchanged or increased by hemorrhage. They concluded that

... in subjects under spinal anesthesia, the power of active vasoconstriction is, however, more or less completely absent because of


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.