The correct treatment of large gastric ulcers is not generally agreed on. The question "Is every large gastric ulcer to be operated on?" has aroused much controversy in the past, and it is still disputed.
In this paper evidence is presented to show that every large gastric ulcer is a condition for operation. This conclusion is not based on the belief that every large gastric ulcer is or may turn into a carcinoma, although that is an important factor. The fact that only a small percentage of large gastric ulcers are malignant or may become malignant should not deter from surgical intervention. Neither the patient who has such a lesion nor the clinician who treats him can be at ease if only 5 per cent or less of such lesions are known to turn malignant.
The difficulty of accurately diagnosing whether a large gastric ulcer is benign or malignant has