SITUS INVERSUS TOTALIS:  A Statistical Review of Data on Seventy-Six Cases with Special Reference To Disease of the Biliary Tract

Arch Surg. 1949;58(5):724-730. doi:10.1001/archsurg.1949.01240030734014.
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"SITUS inversus viscerum" is a term used to designate an anomalous condition in which organs or systems are transposed from their normal sites to locations on the opposite side of the body. It may include complete transposition of both the thoracic and the abdominal viscera or of only one or the other.

Fabricius1 in 1600 reported the first known case of reversal of the liver and spleen in man, and Kuchenmeister2 in 1824 was the first to recognize the condition in a living person. To Vehsemeyer,3 in 1897, is given the credit for being first to demonstrate, by roentgen ray, transposition of the viscera.

During the years 1910 through 1947, of 1,551,047 patients registered at the Mayo Clinic, 76 were found on physical or roentgenologic examination, or both, to have a situs inversus of both thoracic and abdominal viscera. Seven others showed thoracic transposition only, and 4


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