THIS paper reports a rare, malignant complication of ulcerative colitis, namely, fibrosarcoma of the colon. It is becoming increasingly evident, as more statistics are published, that chronic ulcerative colitis in a significant percentage of cases may be complicated by a malignant degeneration of the colon, usually carcinomatous in type.
Lynn,1 in an extensive review of more than 1,400 cases of ulcerative colitis, found that carcinoma developed in 1.9 per cent of the series. Jackman, Bargen and Helmholz2 found an incidence of carcinoma of 6.3 per cent in 95 children with ulcerative colitis. Bargen, Jackman and Kerr3 reported an incidence of 3.2 per cent in a group of 871 patients of all ages. In 450 cases of ulcerative colitis at the Lahey Clinic there was an incidence of carcinoma of 2 per cent.4 Bockus5 reported an incidence of about 1.5 per cent in 200 cases.