THE FUNDAMENTAL information about external pancreatic secretion has been derived in the main from experimental studies on animals, although an occasional report is found in the medical literature about physiologic observations made on human subjects. Opportunity was afforded Wiper and one of us (J. M. M.)1 to study three persons with external pancreatic fistula, and the results of these investigations have been published. A further chance was given to us to repeat and enlarge on the investigations made previously.
An external pancreatic fistula developed subsequent to a surgical procedure for a congenital duplication of the stomach in a 32 year old white man, the subject of this study. The duplication was removed by doing a partial gastrectomy. In the interpretation of the results which are concerned with the usually accepted theory of stimulation of pancreatic secretion, it should be remembered that a large part of the distal portion of