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JOSEPHUS C. LUKE, M.D., F.R.C.S. (Eng., Can.)
AMA Arch Surg. 1950;61(5):787-792. doi:10.1001/archsurg.1950.01250020795001.
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DESPITE the addition of anticoagulant therapy and the judicious use of vein interruption, thrombophlebitis of the deep veins of the leg is still a major problem. This condition not only is an immediate danger but in subsequent years gives rise to many complications which are most difficult to treat. There appears to be a scarcity of knowledge of what happens to the deep veins after such a lesion and especially of what the condition of the venous return is many years later.

In an attempt to shed some light on this problem, 28 cases from the inpatient and the outpatient services of the Royal Victoria Hospital have been investigated by means of retrograde venography of the deep veins of the leg. All the patients had a history of previous deep thrombophlebitis present from 2 to 25 years previously, and all had one or more of the complications of the postphlebitic leg comprising edema,


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