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ARTICLE |

ARE GASTROJEJUNAL ULCERS DUE TO HYPERSECRETION?

Lester R. Dragstedt, M.D.
AMA Arch Surg. 1953;66(5):579-581. doi:10.1001/archsurg.1953.01260030596001.
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GASTROJEJUNAL ulcers began to be observed shortly after the introduction of gastroenterostomy and have remained a serious complication of gastric surgery to the present time. Indeed, success in the treatment of duodenal ulcer is all too often cancelled by the development of a new ulcer in the jejunum adjacent to the anastomosis with the stomach, which may be more disabling and dangerous than the original disease. Recent observations in both the laboratory and the clinic have shed new light on the cause of gastrojejunal ulcer and form the basis for this editorial. The view that gastrojejunal ulcers, along with those occurring in the lower end of the esophagus, the stomach proper, the first portion of the duodenum, and in the ileum near the entrance of a Meckel's diverticulum containing heterotopic gastric mucosa, are peptic ulcers and are due to the corrosive action of the gastric content is widely accepted. The

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