0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

ALPHA-TOCOPHEROL AND ALPHA-TOCOPHEROL PHOSPHATE IN THE PROPHYLAXIS OF THROMBOEMBOLISM

RICHARD H. MOORMAN Jr., M.D.; HOWARD E. SNYDER, M.D.; CECIL D. SNYDER, M.D.; WENDELL A. GROSJEAN, M.D.
AMA Arch Surg. 1953;67(2):137-141. doi:10.1001/archsurg.1953.01260040142003.
Text Size: A A A
Published online

IN THE first seven months of 1949, thromboembolic disease developed postoperatively in nine patients in the surgical service of the Snyder-Jones Clinic, Winfield, Kan., and two of these nine patients died with pulmonary embolism. During the summer of 1949, we learned of the work later reported by Ochsner, DeBakey, and DeCamp, and by Kay and his co-workers1 on blood antithrombin levels and the use of alpha-tocopherol in raising the blood antithrombin levels. Beginning Aug. 1, 1949, an attempt was made to give alpha-tocopherol acetate, 200 mg. every eight hours to all patients undergoing major surgery. Medication was started prior to surgery whenever possible and continued throughout the postoperative period in the hospital. In addition, patients were given calcium gluconate, 10 cc. of a 10% solution intravenously, every 48 hours, starting sometime in 1950. Still later, alpha-tocopherol phosphate became available for intramuscular injection and was prescribed postoperatively in a dose

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();