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MALIGNANT GANGLIONEUROMA OF THE GANGLION NODOSUM OF THE VAGUS NERVE

GEORGE T. PACK, M.D.; IRVING M. ARIEL, M.D.; THEODORE R. MILLER, M.D.
AMA Arch Surg. 1953;67(5):645-660. doi:10.1001/archsurg.1953.01260040656003.
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GANGLIONEUROMAS of the ganglion nodosum of the vagus nerve are extremely rare. Only two such tumors have been recorded to date.1 A third tumor, treated by us, offered an excellent opportunity to study the nature and nosology of these neoplasms. The pertinent features of this unusual oncologic entity are presented here in detail because (1) it is the only malignant ganglioneuroma of the nodose ganglion recorded, (2) the patient is the youngest one in whom a malignant tumor of the nodose ganglion was successfully resected, and (3) the case is the only one recorded in which no permanent defect persisted after resection of a ganglioneuroma of the ganglion nodosum of the vagus nerve. The clinical and pathologic features of this neoplasm involving the nodose ganglion form the subject of this presentation.

REPORT OF A CASE  The patient was an 11I/2-month-old white girl, who suffered from a mass on the

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