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Surgical Experiences with Three Hundred Sixteen Duodenal and Marginal Gastric Ulcers

AMA Arch Surg. 1955;70(6):833-842. doi:10.1001/archsurg.1955.01270120041006.
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Hypersecretion of acid gastric juice has been proved by Dragstedt1 to be a constant factor in patients with duodenal ulcer. The basic etiology underlying this constant is, unfortunately, not proved. Until the etiology is completely understood, as Walters2 has pointed out, the modes of treatment and the results will necessarily vary.

The literature of the past 10 years is replete with excellent contributions, but the surgical field is still rather sharply divided into radical resectionists on the one side and the vagotomists on the other. Both sides are represented by excellent and conscientious men separated only by approach, not by fundamental concept.

Pavlov3 and his group, in 1910, proved beyond question that acid gastric secretion occurs in animals approximately five minutes after the sight, smell, or taste of food, or even the appearance of the feeding attendant. He also proved that this modality was abolished if the


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