The postgastrectomy, or dumping, syndrome is a common and severe complication following total gastrectomy and occurs not infrequently after partial gastrectomy.* Since there has been confusion as to the mechanism of this syndrome, it was decided to study a series of cases. It was our feeling that if the true mechanism could be clearly established proper therapy might then be instituted. For the past two and one-half years a group consisting of members of the surgical physiology unit, the gastric service, and the biochemistry service of the Memorial Center has been studying this problem. Because of the interest by the gastric service in total gastrectomy as the treatment for cancer of the stomach and with this material at hand, the major emphasis of this study has been on this type of patient.
The syndrome consists of a feeling of fullness, churning, or discomfort in the epigastrium, occurring shortly after eating