Reconstruction of the urinary bladder in the experimental animal has been carried out using seromuscular grafts of intestinal origin.* In these studies segments of ileum and colon with intact mesenteric pedicle were stripped of the mucous membrane, reversed so that the serosa faced inward, and sutured to a trigonal remnant. The present study concerns observations on the changes of the aging seromuscular graft, ileal grafts with intact mucous membrane, ileal grafts stripped of the mucous membrane but not reversed, and ileal grafts in which the mucosa and the submucosa were removed, leaving only the raw muscularis facing toward the lumen.
MATERIALS AND METHODS
The technique of bladder reconstruction by means of seromuscular grafts, according to an original method, has been described in detail.3 Since the first published series of 10 dogs, three additional types of experimental conditions were performed on a total of 31 animals for comparative purposes. These