Arterial Homografts in Immediate Treatment of Severe Injuries to a Major Artery

AMA Arch Surg. 1957;74(4):555-556. doi:10.1001/archsurg.1957.01280100073011.
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Since the first successful end-to-end anastomosis of a severed femoral vessel by Murphy 56 years ago, tremendous progress has been made in the surgical treatment of vascular diseases. None were more important or dramatic than the advances made in the successful repair of acute arterial injuries during the Korean conflict.1 Thus, prior to 1952, injuries to major arteries were treated almost routinely by ligation. Even when primary anastomoses were attempted, results were seldom successful. An incidence of amputation due to gangrene of 62% was reduced following the institution of a successful program of arterial repair to 7%.2 Although the proportion of civilian injuries due to penetrating wounds is smaller than in war casualties, the annual number of civilian accidents is increasing and necessarily entails many types of vascular injuries by a large number of persons. The National Safety Council recently reported approximately ten million civilian accidents a year,


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