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A Case of Islet-Cell Carcinoma of the Pancreas Associated with Peptic Ulceration f the Jejunum

AMA Arch Surg. 1957;74(5):703-708. doi:10.1001/archsurg.1957.01280110045007.
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Carcinoma of the pancreatic islet cells remains a very unusual tumor. There are few reports of attempted resection. The case report which follows concerns a 37-year-old white man who has remained well for two years and three months after resection of the stomach and pancreaticoduodenectomy for a nonfunctioning metastasizing islet-cell carcinoma of the pancreas with associated jejunal ulceration.

Report of Case  A 37-year-old white male farmer was admitted to the hospital in August, 1954, with complaints of itching skin and pain in the upper abdomen. One year previously a subtotal gastrectomy and gastrojejunostomy were done for an ulcer in the first part of the duodenum. His convalescence was without incident, and he remained well for a period of about eight months. He then began having burning epigastric pain, and shortly thereafter a marginal ulcer was demonstrated by x-ray examination. Jaundice was first noted two months before admission, and about the


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