We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Investigations on Adsorption of Benzalkonium Chloride U. S. P. by Skin, Gloves, and Sponges

AMA Arch Surg. 1957;75(6):1036-1042. doi:10.1001/archsurg.1957.01280180168027.
Text Size: A A A
Published online


Introduction  The wide clinical use of benzalkonium chloride U. S. P. as a germicide makes the investigation of its adsorption on articles immersed in it of practical, as well as theoretical, significance. Sporadic instances of isolation of bacteria from solutions supposedly containing benzalkonium have occurred. Subsequent tests on isolated organisms have shown them to be sensitive to the quaternary, indicating that their survival may have been due to a depletion of the germicide from the original solution.A number of investigators have described the adsorption of quaternaries upon textiles. Goldsmith et al.1 reported that chlorine and benzalkonium chloride are removed from solution by wool and cotton fabrics to a degree, depending on original concentrations. Fischer and Seidenberg2 noted a definite correlation between antibacterial activity of water-soluble substances and their affinity for wool, a greater affinity representing a higher bactericidal action. Two quaternary compounds, Sapamine KW Concentrate (quaternary ammonium


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.