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Limitations of Synthetic Fabrics as Peritoneal Substitutes

AMA Arch Surg. 1958;76(4):593-598. doi:10.1001/archsurg.1958.01280220113023.
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The use of foreign substances to reinforce hernial repairs is almost commonplace today. Most popular among these materials are mesh screens of tantalum or steel and cloths made of synthetic yarns, such as Fortisan, nylon, and Dacron. In addition to their immediate function as structural supports, these substances further strengthen the closure by becoming enmeshed in fibrous tissue as time goes along. It is well known that no foreign substance is as well tolerated as the host's own tissues. Adequate surgical repair of some defects, however, is possible only with the use of substitute materials. Occasionally in clinical surgery it is necessary for the patch of foreign substance to come in direct contact with the serosal surfaces of underlying bowel, as, for example, after extensive resection of the diaphragm, pelvic peritoneum, or all abdominal-wall layers for malignancy, or when mural structures cannot be approximated for other reasons. No material has


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