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Incomplete Rupture of the Colon Following Hydrogen Peroxide Enema

LOUIS G. LUDINGTON, M.D.; SHERMAN W. HARTMAN, M.D.; JAMES E. KEPLINGER, M.D.; FRANK S. WILLIAMS, M.D.
AMA Arch Surg. 1958;76(4):658-660. doi:10.1001/archsurg.1958.01280220178036.
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An unusual case of incomplete rupture of the sigmoid and transverse colon following a hydrogen peroxide enema is presented. Examination of the medical literature failed to reveal a similar case, though there have no doubt been others. This case is recorded to show the danger of injecting hydrogen peroxide solutions into closed body cavities and as an interesting and unusual cause of incomplete rupture of the colon.

Report of Case  A 62-year-old white man with a 15-year history of peptic ulcer was admitted to the Wadsworth Hospital on May 7, 1957, because of weakness, syncope, and hematemesis six days prior to admission. On admission, his hemoglobin was 10.7 gm. per 100 cc., having dropped from 12.6 gm. a few days earlier. A review of his past history revealed a previous bleeding episode 10 years earlier. He had had known hypertension three years and symptoms of angina pectoris for the same

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