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Virchow's Metamorphosis of the Salivary Glands

AMA Arch Surg. 1958;77(1):110-112. doi:10.1001/archsurg.1958.01290010112020.
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In Virchows Archiv,1 the term fatty infiltration is described, but the emphasis is appropriated primarily to the liver and the pancreas. The general description is readily applicable to other glandular organs. The condition with respect to the salivary glands in the cases to be reported has not been accompanied by symptoms to any great extent other than those symptoms which may accompany a generalized increase in the lipid accumulation throughout the body. It is understandable, however, that if the infiltration is great enough, a state of functional insufficiency in the gland will occur, due to the crowding out of active secreting cells or groups of cells in the organ involved. This condition may, therefore, manifest symptoms, but as a whole is a matter of differential interest only. The problem of diagnosis is the prime consideration. An approach following logical elimination of worthy practical pathology is made before surgery is


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