Relationship of Exophthalmos to Disorders of the Thyroid

AMA Arch Surg. 1958;77(1):130-143. doi:10.1001/archsurg.1958.01290010132024.
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Analysis of Data on Proptosis (74 Patients)  The average period of serial observations is 11 years, the shortest 2, and the longest 20. Changes of 1 mm. are disregarded in using the Luedde or other "ruler" types of exophthalmometers.1. During the uniform improvement in metabolic status and in appearance of the eyes that occurred during preoperative treatment, increase of proptosis was found as often as decrease.2. Decrease occurred in only 10% of patients between preoperative measurements and those made during four months postoperatively. No correlation was found with the rapidity or quantity of metabolic improvement.3. Decrease in 16% and increase in 71% of patients occurred between the early period of observation and the final. Patients less than 30 years of age were most apt to show improvement.4. Range of final measurements in 59 instances revealed bilateral proptosis of 18 mm. or less in 15% and of


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