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ARTICLE |

Clinical Application of a New Flexible Knitted Dacron Arterial Substitute

MICHAEL E. DE BAKEY, M.D.; DENTON A. COOLEY, M.D.; E. STANLEY CRAWFORD, M.D.; GEORGE C. MORRIS Jr., M.D.
AMA Arch Surg. 1958;77(5):713-724. doi:10.1001/archsurg.1958.01290040061008.
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ABSTRACT

The direct surgical treatment of various forms of aortic and arterial disease often requires a vascular replacement. Homografts were first employed successfully for this purpose and both technically and functionally have provided gratifying results. Their major disadvantage, however, lies in the inconvenience associated with their procurement and preparation, and the fact that they are not available in sufficient quantities to meet the increasing demands for their use. For these reasons attention has been directed toward development of a satisfactory arterial substitute for homografts which would be free of these disadvantages. In cooperation with Prof. Thomas Edman, of the Philadelphia Textile Institute, a new flexible knitted Dacron tube has been devised which on the basis of experimental and clinical studies has been found to meet this objective. Among its desirable characteristics are the following: First, it may be repeatedly sterilized by autoclaving in the usual manner without harm to or weakening

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