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Two Cases of Leiomyosarcoma of the Duodenum

AMA Arch Surg. 1960;80(3):528-532. doi:10.1001/archsurg.1960.01290200172031.
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Since the first report of leiomyosarcoma of the duodenum in 1920, approximately 60 cases have been described.5 The number of patients in whom the tumor was successfully removed has, however, been small. Many of the reported cases were first diagnosed at autopsy, and others were nonresectable at the time of operation. In addition, the mortality rate in the early attempts at resection was high, being approximately 70% in the collected series of Weinstein and Roberts6 in 1953.

The purpose of the present report is to document two additional examples of successfully treated leiomyosarcoma of the duodenum. In one patient a tumor in the fourth part of the duodenum was removed with segmental resection. The neoplasm in the other patient was in the second part of the duodenum, necessitating pancreaticoduodenal resection.

Report of Cases 

Case 1 (Veterans Administration Hospital, Chicago).  —This 42-year-old white man was admitted to the hospital


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